BIOFABRICATION



The Biofabrication and Tissue Engineering branch of the OMFS-IMPATH Research Group focuses on the upcoming field of regenerative dentistry.


We are dedicated to overcoming the limitations of current dental materials by developing advanced biofabrication techniques that pave the way for more personalized medicine.


Our goal is to create innovative, long-lasting dental solutions that maintain dental tissue vitality, ensuring healthier, more durable results for patients.

Mostafa Ezeldeen

mostafa.ezeldeen@kuleuven.be

Prof. Reinhilde Jacobs

reinhilde.jacobs@kuleuven.be

Related projects and publications

Project 6: iDentgel


Researchers: U. Ivković


Project explained - Science Figured Out: https://youtu.be/4vodaMt9hxU


Publiction: in progress


Graphical abstract iDentgel - simplified

Project 5: Biofabrication of engineered dento-alveolar tissue


Researchers: M. EzEldeen, L. Moroni, Z. M. Nejad, R. Jacobs, C. Mota


Published on:

EzEldeen M, Moroni L, Nejad Z M, Jacobs R, Mota C. Biofabrication of engineered dento-alveolar tissue, Biomaterials Advances, 2023, 213371, ISSN 2772-9508, https://doi.org/10.1016/j.bioadv.2023.213371.


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Project 4: The development of a 3D printable chitosan-based copolymer with tunable properties for dentoalveolar regeneration


Researchers: M. Salar Amoli, R. Anand, M. EzEldeen, P.A. Amorim, L. Geris, R. Jacobs, V. Bloemen 


Published on:

Salar Amoli M, Anand R, EzEldeen M, Amorim PA, Geris L, Jacobs R, Bloemen V. The development of a 3D printable chitosan-based copolymer with tunable properties for dentoalveolar regeneration. Carbohydr Polym. 2022 Aug 1;289:119441. doi: 10.1016/j.carbpol.2022.119441. Epub 2022 Apr 2. PMID: 35483854.


Project 3: Chlorite oxidized oxyamylose differentially influences the microstructure of fibrin and self assembling peptide hydrogels as well as dental pulp stem cell behavior


Researchers: M. EzEldeen, B. Toprakhisar, D. Murgia, N. Smisdom, O. Deschaume, C. Bartic, H. Van Oosterwyck, R.V.S. Pereira, G. Opdenakker, I. Lambrichts, A. Bronckaers, R. Jacobs, J. Patterson


Published on:

EzEldeen M, Toprakhisar B, Murgia D, Smisdom N, Deschaume O, Bartic C, Van Oosterwyck H, Pereira RVS, Opdenakker G, Lambrichts I, Bronckaers A, Jacobs R, Patterson J. Chlorite oxidized oxyamylose differentially influences the microstructure of fibrin and self assembling peptide hydrogels as well as dental pulp stem cell behavior. Sci Rep. 2021 Mar 11;11(1):5687. doi: 10.1038/s41598-021-84405-4. PMID: 33707502; PMCID: PMC7952722.


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Project 2: 3D-printing-assisted fabrication of chitosan scaffolds from different sources and cross-linkers for dental tissue engineering


Researchers: M. EzEldeen, J. Loos, Z. Mousavi Nejad, M. Cristaldi, D. Murgia, A. Braem, R. Jacobs


Published on:

EzEldeen M, Loos J, Mousavi Nejad Z, Cristaldi M, Murgia D, Braem A, Jacobs R. 3D-printing-assisted fabrication of chitosan scaffolds from different sources and cross-linkers for dental tissue engineering. Eur Cell Mater. 2021 May 5;41:485-501. doi: 10.22203/eCM.v041a31. PMID: 33948929.


Project 1: Materials for Dentoalveolar Bioprinting: Current State of the Art


Researchers: M. Salar Amoli, M. EzEldeen, R. Jacobs, V. Bloemen


Published on:

Salar Amoli M, EzEldeen M, Jacobs R, Bloemen V. Materials for Dentoalveolar Bioprinting: Current State of the Art. Biomedicines. 2021 Dec 30;10(1):71. doi: 10.3390/biomedicines10010071. PMID: 35052751; PMCID: PMC8773444.


Materials for dentoalveolar bioprinting_1
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