Rocharles Cavalcante Fontenele was born in Jaguaretama, Ceara, Brazil, in 1995. He earned his dental degree in 2016 at the Federal University of Ceara, Brazil. Subsequently, he obtained his master's and Ph.D. in Oral Radiology at the University of Campinas (UNICAMP) in 2018 and 2023, respectively. During his Ph.D., he received a scholarship from the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Brazilian government) to collaborate with the OMFS-IMPATH research group under the supervision of Prof. Dr. Reinhilde Jacobs. His research primarily focused on Artificial Intelligence-driven segmentation of dental and bone structures in cone-beam computed tomography images.

Since 2023, he has been a postdoctoral researcher at Katholieke Universiteit Leuven (KU Leuven) under the supervision of Prof. Dr. Reinhilde Jacobs, where he coordinates the AI research projects developed by the OMFS-IMPATH research group. His research focuses on AI-driven segmentation in CBCT images, 2D and 3D imaging diagnosis, CBCT image quality, and artifacts in CBCT images.

He has published 50 peer-reviewed articles in important journals in the Dentistry, Oral Surgery & Medicine area, such as Dentomaxillofacial Radiology, Clinical Oral Investigations, Journal of Dentistry, Journal of Endodontics, International Endodontic Journal, and Clinical Oral Implants Research. Additionally, he has received 35 awards during his postgraduate courses, including ones granted by the European Academy of DentoMaxilloFacial Radiology, Digital Dentistry Society, and IADR-Brazilian section.